Clinical Trials

Blue Faery: The Adrienne Wilson Liver Cancer Association



Clinical Trials

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Clinical trials are studies conducted on volunteers using investigational treatments or methods. The decision to enroll in a trial should be based on concrete information and eligibility depends on many factors. For more information about HCC clinical trials in your area, visit

  • Discuss the advantages, disadvantages and side effects of treatment options with your doctor.
  • Ask your doctor about the possibility of using experimental therapies and eligibility to participate in clinical trials. If you want to participate in clinical trial, ask what is the phase of the trial.
  • Consider seeking a second opinion if your health insurance allows you the option to do so.

Liver Cancer Clinical Trials (featured listings)

An Open-Label Multicenter Phase 1 Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of H3B-6527 in Subjects With Advanced Hepatocellular Carcinoma*

The primary purpose of this study is to determine the maximum tolerated dose (MTD) and recommended Phase 2 dose (RP2D) of H3B-6527 (Part 1), and to assess the safety and tolerability of H3B-6527 as a single agent administered orally (Part 2) in participants with advanced hepatocellular carcinoma (HCC).

Condition: Hepatocellular carcinoma
Intervention: Dose Escalation
Phase: Phase I
Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Primary Purpose: Objective tumor response

For more information, email

H3 Biomedicine with Eisai Inc
300 Technology Square, 5th Floor
Cambridge, MA 02139
United States
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Business Phone: (888) 274-2378

Surefire vs. Endhole for DEB-TACE: Quantifying Hepatic Artery Embolization to Improve Outcomes by Comparing Two Different Catheter Systems for DEB-TACE (QED Study)*

This project involves the collection and analysis of retrospective and prospective data on patients diagnosed with hepatocellular carcinoma (HCC) in which the Surefire Precision Infusion System was used/will used be to deliver transarterial chemoembolization with doxorubicin-eluting beads (DEB-TACE). The purpose is to compare tumor and medical response in a real-world setting as well as identify potential areas for future clinical research.

Condition: Hepatocellular carcinoma
Intervention: Device: DEB-TACE with Surefire Precision Infusion System. Subjects have undergone/will undergo DEB-TACE using the Surefire Precision Infusion System.
Phase: 4 (Post-Market)
Study Type: Observational [Patient Registry]/Industry-Sponsored Interventional
Study Design: Observational Model: Case-Only
Primary Purpose: Objective tumor response

For more information, email John Ferraro.

Surefire Medical, Inc.
John Ferraro, Vice President, Clinical Operations
6272 W 91st Ave
Westminster, CO 80031
United States
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Business Phone: (303) 929-0208
Cell Phone: (303) 929-0208

A Phase 3, Randomized, Double-blind, Controlled Study of Cabozantinib (XL184) vs Placebo in Subjects With Hepatocellular Carcinoma Who Have Received Prior Sorafenib*

This study is investigating a therapy called cabozantinib for the treatment of advanced hepatocellular carcinoma, the most common form of liver cancer, in adults whose disease has spread or grown after treatment with the medication sorafenib. The main purpose of the CELESTIAL trial is to determine whether cabozantinib can improve patient survival.

Condition: Hepatocellular carcinoma
Intervention: Cabozantinib
Phase: 3
Study Type: Interventional
Study Design: Allocation: Randomized; Intervention Model: Parallel Assignment; Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor)
Primary Purpose: Treatment

For more information, email or call 1-855-292-3935

Exelisis, Inc
Lindsay Treadway, Director, Public Affairs and Advocacy Relations
210 East Grand Avenue
South San Francisco, CA 94080
United States
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Phone: (650) 837-7522

*Indicates a paid listing

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