Liver Cancer News

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Biomarkers To Detect And Prevent Liver Cancer
31 October 2018
In patients with precancerous cirrhotic livers, there may be a new identifier for researchers to help stop the development of liver cancer. By being able to pinpoint when the cirrhosis progresses to cancer, there would be an improvement in early detection and treatment for patients. The researchers are hopeful that this new marker may improve HCC survival.

Property Developer Accused Of Firing Employee Over Cancer
28 October 2018
A liver cancer patient who was fired from his job due to health discrimination. The patient wrote a complaint to the Human Rights Commission based on how he was let go from the company and not given his owed compensation because of his diagnosis of liver cancer. The company is a multi-billion dollar real estate developing company in Australia.

Utoledo Research Finds Link Between Refined Dietary Fiber, Gut Bacteria And Liver Cancer
18 October 2018
Through research at the University of Toledo, interesting results have been found regarding how processed dietary fibers may be inducing liver cancer. The way our gut bacteria breaks down this specific type of fiber is thus connected to the liver cancer risk. Dr. Vijay-Kumar says, “Our study is going against the conventional wisdom of what people think, that fiber is good, no matter how they get it. We do not want to promote that fiber is bas. Rather, we highlight that fortifying processed foods with refined soluble fiber may not be safe or advisable to certain individuals with gut bacterial overgrowth or dysbiosis, whose abnormal fermentation of this fiber could increase the susceptibility to liver cancer.”

Brewing Up A Healthy Lifestyle: Coffee And Body Fat Reduce Liver Cancer Risk
17 October 2018
“There is strong evidence that greater body fat, consumption of alcoholic drinks and eating foods contaminated with aflatoxins increase the risk of liver cancer,” according to AICR’s recently released Diet and Cancer Report. There is strong evidence that lifestyle factors play important roles in the possible increase risk of liver cancer. These factors are particular to what a person eats and drinks.

Low PNI Predicts Poor Liver Cancer Outcomes: Meta-Analysis Supports Prognostic Tool For Hepatocellular Carcinoma
16 October 2018
Researchers at Zhengzhou University in China created a meta-analysis of Asian studies on the ability for the prognostic nutritional index (PNI) to predict outcomes in HCC. Wang and his associates said ‘these pooled results suggested that high PNI is beneficial to the survival of HCC patients and associated with more favorable outcomes such as lower AFP, lower reoccurrence, minor tumor size, and better TNM’. It is important to note there were limitations with the study; however, the conclusion stands.

Liver Cancer Treatment Paradigm Undergoing Major Overhaul
15 October 2018
In the past few months, there has been a significant resurgence in the development of new HCC medications. For example, Lenvima was approved in August 2018 as a first-line treatment for patients with unresectable HCC as well as the accepted supplemental new drug application for Cabometryx in May of 2018. The expectation for patient survival is increasing with the positive results of clinical trials for these new medications, thus bringing new hope to patients.

Variable RBE Impacts Proton Therapy Of Liver Cancer
15 October 2018
Proton therapy offers the advantage of affecting less of the healthy liver tissues in HCC patients. “Radiation therapy for Hepatocellular Carcinoma is currently being investigated in several clinical trials, including proton therapy.” There is still too much uncertainty to readily use this therapy in patients, based on the variability that it has provided thus far.

Ongoing Trial Exploring Oncolytic Virus Pexa-Vec In HCC
8 October 2018
There is a phase 3 clinical trial that is comparing the use of Pexa-Vec and then Nexavar versus treatment with only Nexavar with the primary endpoint of the study being overall survival (OS). The researchers are currently recruiting for the PHOCUS trial and are looking for ‘600 patients with advanced HCC who have not received prior systemic therapy’.

Lower Liver Cancer Risk Seen With Tenotovir Treatment Of Chronic Hepatitis B
4 October 2018
“The risk of Hepatocellular Carcinoma (HCC) in patients with chronic hepatitis B (CHB) treated with tenofovir is lower than in those treated with entecavir, according to a nationwide study from South Korea.” The researchers mention that this information is only one observational study and more studies are needed.

Regular Aspirin Use Can Lower Risk For Ovarian, Liver Cancers
4 October 2018
Two studies from the Nurses’ Health Studies have shown a significant reduction of risk for HCC. The data was collected from nearly 90,000 women and nearly 46,000 men since the 1980s. “A regular dose of aspirin at least two or more times per week was associated with a 49 percent reduced risk of developing the disease. The observed benefit of aspirin was dose and duration dependent, appearing with aspirin use for five years or more, at a dose of 1.5 or more standard tablets per week.”

For HCV Patients, New Online Calculator Predicts HCC Risk After Treatment
3 October 2018
After using direct-acting antivirals (DAAs), patients with Hepatitis C may gain a response or no response. If there is a response, that information can be used in this new online calculator to assess the risk for HCC development in the future.

For past liver cancer news, please visit our Liver Cancer News Archives.

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