An older chemotherapy drug, fluorouracil is used for many types of cancer, including liver cancer, and can be administered intravenously and orally. (In skin cancer it can be used as a crème applied directly to the skin.) The most common cancers that use this drug include colon, rectal, and breast cancer. It is prescribed to liver cancer patients. Fluorouracil is an antineoplastic antimetabolite, and is chemically 5-fluoro-2,4(1H,3H)-pyrimidinedione with molecular formula C4H3FN2O2. Possible side effects of fluorouracil can include: mouth sores, ulcers, diarrhea, blurry vision, skin irregularities and sensitivity, impaired bone marrow function, vomiting, hair loss, brittle nails, and rashes.